When active, it drains Eve's health to summon Blood Clot familiars while she is shooting tears.
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This is a special item you'll be able to grab in the biome Depths II. You'll need to find Dad's Note on another run. This is a new boss added to the Repentance DLC, and you'll find her at the end of the Corpse II biome. You'll need to defeat Mother at least once.
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However, it is time consuming if you want to catch 'em all, and you need to string together a good run in order to reach the point where you can access them. Unlocking tainted characters is simple to explain, as the process is the same for each one.